In news that may be of interest to those seeking Alzheimer's care or advice for themselves or a family member, the study - set to be published in the Journal of the American Medical Association - recommended that people suffering from the condition did not take the supplement.
This is because scientists now believe that vitamin B can lower the levels of a specific amino acid which is linked to brain cell damage that appears similar to that found in patients with the disease.
Lead author Paul Aisen, a professor in the department of neurosciences at the University of California San Diego, said: "People should recognize that it is likely that an unproven treatment will cause as much harm as benefit, even if it's available as a supplement in a pharmacy or health foods store."
According to Bloomberg, 5.2 million Americans now live with Alzheimer's disease, which is the sixth leading cause of death.
Meanwhile, new research has revealed that moderate exercise - such as aerobics - may delay or even reverse the onset of mental decline, the British newspaper the Telegraph has reported.
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